Can the NVIDIA RTX 3080 10GB run Mixtral 8x7B?

No

No. Even at Q4_K_M, Mixtral 8x7B needs about 30 GB, but the NVIDIA RTX 3080 10GB has 10 GB usable. You could offload some layers to system RAM, but it will be very slow.

Try other context lengths in the calculator →
Run it in the cloud

Too big for the NVIDIA RTX 3080 10GB? Run Mixtral 8x7B on a rented GPU instead.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality95.1 GBToo big—
Q8_0Near-lossless51.3 GBToo big—
Q6_KExcellent40 GBToo big—
Q5_K_MVery good34.9 GBToo big—
Q4_K_MGood, most popular30 GBToo big—
Q3_K_MNoticeably degraded24.5 GBToo big—
Q2_KHeavily degraded19.2 GBToo big—

How to run Mixtral 8x7B anyway

On a rented cloud GPU with enough memory, the same command you'd use locally works:

ollama run mixtral:8x7b

At Q4_K_M it needs about 30 GB, so pick a GPU with at least 32 GB.

GPUs that run Mixtral 8x7B comfortably

Check NVIDIA RTX 5090 prices →

Models that run well on the NVIDIA RTX 3080 10GB