Can the NVIDIA RTX 4080 run Qwen3 8B?

Yes
QuantQ8_0Near-lossless
Memory10.5 GBof 16 GB
Speed~49tokens/s

Yes. The NVIDIA RTX 4080 can run Qwen3 8B fully in VRAM at Q8_0 (near-lossless), using about 10.5 GB of the 16 GB available, at roughly 49 tokens/second.

Try other context lengths in the calculator →

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality18.2 GBToo big—
Q8_0Near-lossless10.5 GBFits~49 tok/s
Q6_KExcellent8.5 GBFits~64 tok/s
Q5_K_MVery good7.6 GBFits~74 tok/s
Q4_K_MGood, most popular6.8 GBFits~87 tok/s
Q3_K_MNoticeably degraded5.8 GBFits~107 tok/s
Q2_KHeavily degraded4.9 GBFits~140 tok/s

How to run Qwen3 8B on the NVIDIA RTX 4080

With Ollama installed, one command downloads and starts it:

ollama run qwen3:8b

Ollama's default download is Q4_K_M (about 6.8 GB here). You have room for Q8_0, which is near-lossless: pick that GGUF in LM Studio or from Hugging Face.

GPUs that run Qwen3 8B comfortably

Models that run well on the NVIDIA RTX 4080

Run it in the cloud

Don't want to buy hardware? Run Qwen3 8B on a rented GPU today.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.