Can the NVIDIA RTX 4090 run Mixtral 8x7B?

Yes, with heavy quantization
QuantQ2_KHeavily degraded
Memory19.2 GBof 24 GB
Speed~125tokens/s

Only just. Mixtral 8x7B fits on the NVIDIA RTX 4090 at Q2_K, which costs noticeable quality. Expect about 125 tokens/second. A card with more memory is a better experience.

Try other context lengths in the calculator →
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Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality95.1 GBToo big—
Q8_0Near-lossless51.3 GBToo big—
Q6_KExcellent40 GBToo big—
Q5_K_MVery good34.9 GBToo big—
Q4_K_MGood, most popular30 GBToo big—
Q3_K_MNoticeably degraded24.5 GBToo big—
Q2_KHeavily degraded19.2 GBFits~125 tok/s

How to run Mixtral 8x7B on the NVIDIA RTX 4090

Ollama's default mixtral:8x7b download is Q4_K_M, which needs about 30 GB, more than the 24 GB available. Download the Q2_K GGUF instead (LM Studio lists quants per model), or try a smaller context length.

GPUs that run Mixtral 8x7B comfortably

Check NVIDIA RTX 5090 prices →

Models that run well on the NVIDIA RTX 4090