Can the NVIDIA RTX 5090 run Gemma 3 27B?

Yes
QuantQ6_KExcellent
Memory27.2 GBof 32 GB
Speed~48tokens/s

Yes. The NVIDIA RTX 5090 can run Gemma 3 27B fully in VRAM at Q6_K (excellent), using about 27.2 GB of the 32 GB available, at roughly 48 tokens/second.

Try other context lengths in the calculator →

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality59.6 GBToo big—
Q8_0Near-lossless33.9 GBToo big—
Q6_KExcellent27.2 GBFits~48 tok/s
Q5_K_MVery good24.2 GBFits~55 tok/s
Q4_K_MGood, most popular21.4 GBFits~65 tok/s
Q3_K_MNoticeably degraded18.2 GBFits~80 tok/s
Q2_KHeavily degraded15 GBFits~105 tok/s

How to run Gemma 3 27B on the NVIDIA RTX 5090

With Ollama installed, one command downloads and starts it:

ollama run gemma3:27b

Ollama's default download is Q4_K_M (about 21.4 GB here). You have room for Q6_K, which is excellent: pick that GGUF in LM Studio or from Hugging Face.

GPUs that run Gemma 3 27B comfortably

Models that run well on the NVIDIA RTX 5090

Run it in the cloud

Don't want to buy hardware? Run Gemma 3 27B on a rented GPU today.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.