Can the NVIDIA RTX 5090 run Mistral 7B v0.3?

Yes
QuantFP16Full quality
Memory16.2 GBof 32 GB
Speed~74tokens/s

Yes. The NVIDIA RTX 5090 can run Mistral 7B v0.3 fully in VRAM at FP16 (full quality), using about 16.2 GB of the 32 GB available, at roughly 74 tokens/second.

Try other context lengths in the calculator →

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality16.2 GBFits~74 tok/s
Q8_0Near-lossless9.4 GBFits~140 tok/s
Q6_KExcellent7.6 GBFits~181 tok/s
Q5_K_MVery good6.8 GBFits~209 tok/s
Q4_K_MGood, most popular6.1 GBFits~245 tok/s
Q3_K_MNoticeably degraded5.2 GBFits~303 tok/s
Q2_KHeavily degraded4.4 GBFits~395 tok/s

How to run Mistral 7B v0.3 on the NVIDIA RTX 5090

With Ollama installed, one command downloads and starts it:

ollama run mistral:7b

Ollama's default download is Q4_K_M (about 6.1 GB here). You have room for FP16, which is full quality: pick that GGUF in LM Studio or from Hugging Face.

GPUs that run Mistral 7B v0.3 comfortably

Models that run well on the NVIDIA RTX 5090

Run it in the cloud

Don't want to buy hardware? Run Mistral 7B v0.3 on a rented GPU today.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.