Can the NVIDIA RTX 5090 run Mistral Small 24B?

Yes
QuantQ8_0Near-lossless
Memory27 GBof 32 GB
Speed~43tokens/s

Yes. The NVIDIA RTX 5090 can run Mistral Small 24B fully in VRAM at Q8_0 (near-lossless), using about 27 GB of the 32 GB available, at roughly 43 tokens/second.

Try other context lengths in the calculator →

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality49.1 GBToo big—
Q8_0Near-lossless27 GBFits~43 tok/s
Q6_KExcellent21.3 GBFits~56 tok/s
Q5_K_MVery good18.7 GBFits~64 tok/s
Q4_K_MGood, most popular16.2 GBFits~75 tok/s
Q3_K_MNoticeably degraded13.5 GBFits~93 tok/s
Q2_KHeavily degraded10.8 GBFits~121 tok/s

How to run Mistral Small 24B on the NVIDIA RTX 5090

With Ollama installed, one command downloads and starts it:

ollama run mistral-small:24b

Ollama's default download is Q4_K_M (about 16.2 GB here). You have room for Q8_0, which is near-lossless: pick that GGUF in LM Studio or from Hugging Face.

GPUs that run Mistral Small 24B comfortably

Models that run well on the NVIDIA RTX 5090

Run it in the cloud

Don't want to buy hardware? Run Mistral Small 24B on a rented GPU today.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.