Can the NVIDIA RTX 3080 10GB run Gemma 3 27B?

No

No. Even at Q4_K_M, Gemma 3 27B needs about 21.4 GB, but the NVIDIA RTX 3080 10GB has 10 GB usable. You could offload some layers to system RAM, but it will be very slow.

Try other context lengths in the calculator →
Run it in the cloud

Too big for the NVIDIA RTX 3080 10GB? Run Gemma 3 27B on a rented GPU instead.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.

Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality59.6 GBToo big—
Q8_0Near-lossless33.9 GBToo big—
Q6_KExcellent27.2 GBToo big—
Q5_K_MVery good24.2 GBToo big—
Q4_K_MGood, most popular21.4 GBToo big—
Q3_K_MNoticeably degraded18.2 GBToo big—
Q2_KHeavily degraded15 GBToo big—

How to run Gemma 3 27B anyway

On a rented cloud GPU with enough memory, the same command you'd use locally works:

ollama run gemma3:27b

At Q4_K_M it needs about 21.4 GB, so pick a GPU with at least 24 GB.

GPUs that run Gemma 3 27B comfortably

Check NVIDIA RTX 3090 prices →

Models that run well on the NVIDIA RTX 3080 10GB