Can the NVIDIA RTX 4080 run Gemma 3 27B?

Yes, with heavy quantization
QuantQ2_KHeavily degraded
Memory15 GBof 16 GB
Speed~42tokens/s

Only just. Gemma 3 27B fits on the NVIDIA RTX 4080 at Q2_K, which costs noticeable quality. Expect about 42 tokens/second. A card with more memory is a better experience.

Try other context lengths in the calculator →
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Memory needed by quantization

At 8,192 tokens of context.

QuantQualityMemoryFits?Speed
FP16Full quality59.6 GBToo big—
Q8_0Near-lossless33.9 GBToo big—
Q6_KExcellent27.2 GBToo big—
Q5_K_MVery good24.2 GBToo big—
Q4_K_MGood, most popular21.4 GBToo big—
Q3_K_MNoticeably degraded18.2 GBToo big—
Q2_KHeavily degraded15 GBFits~42 tok/s

How to run Gemma 3 27B on the NVIDIA RTX 4080

Ollama's default gemma3:27b download is Q4_K_M, which needs about 21.4 GB, more than the 16 GB available. Download the Q2_K GGUF instead (LM Studio lists quants per model), or try a smaller context length.

GPUs that run Gemma 3 27B comfortably

Check NVIDIA RTX 3090 prices →

Models that run well on the NVIDIA RTX 4080